Relationship between chronic inflammation and depression : search for biomarkers and possible drug targets
Boter Carbonell, Clara
Martínez Cáceres, Eva María, dir. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Universitat Autònoma de Barcelona. Facultat de Medicina

Date:	2016
Description:	34 pag.
Abstract:	It has been predicted that depression will become the second-leading cause of disability worldwide after human immunodeficiency virus (HIV) in 2030. Numerous recent data suggest an important role of inflammation in patients with depressive disorder. In fact, there has been found an increase of inflammatory markers in some depressed patients and the administration of pro-inflammatory cytokines or their inducers has been shown to cause symptoms of depression. Besides this, it has been discovered that patients with chronic inflammatory diseases (rheumatoid arthritis, psoriasis, inflammatory bowel disease . . . ) show a higher prevalence of depression. Therefore, we hypothesize that manifestations of depression are related to chronic inflammation, at least in some patients with major depressive disorder. Thereby, an anti-inflammatory treatment may improve symptoms of depression. The general objective of this study is to analyse the relationship between inflammation and major depressive disorder (MDD) and search for potential diagnostic biomarkers and therapeutic targets.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Language:	Anglès
Studies:	Medicina [250442]
Study plan:	Grau en Medicina [1192]
Document:	Treball final de grau ; Text
Subject:	Medicina

34 p, 1.3 MB

The record appears in these collections:
Research literature > Bachelor's degree final project > Medicine Faculty