An inkjet-printed field-effect transistor for label-free biosensing

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(Institut Català de Nanociència i Nanotecnologia)
Martínez-Domingo, Carme

(Institut Català de Nanociència i Nanotecnologia)
Ramon, Eloi

(Institut de Microelectrònica de Barcelona)
Merkoçi, Arben

(Institut Català de Nanociència i Nanotecnologia)

Data:	2014
Resum:	A flexible, biological field-effect transistor (BioFET) for use in biosensing is reported. The BioFET is based on an organic thin-film transistor (OTFT) fabricated mainly by inkjet printing and subsequently functionalized with antibodies for protein recognition. The BioFET is assessed for label-free detection of a model protein, human immunoglobulin G (HIgG). It is characterized electrically to evaluate the contribution of each step in the functionalization of the OTFT and to detect the presence of the target protein. The fabrication, structure, materials optimization, electrical characteristics, and functionality of the starting OTFT and final BioFET are also discussed. Different materials are evaluated for the top insulator layer, with the aim of protecting the lower layers from the electrolyte and preserving the BioFET electrical performance.
Ajuts:	European Commission 246513 Ministerio de Ciencia e Innovación TEC2011-29800 Ministerio de Ciencia e Innovación MAT2011-25870
Drets:	Tots els drets reservats.
Llengua:	Anglès
Document:	Article ; recerca ; Versió acceptada per publicar
Matèria:	Electrical characteristic ; Electrical performance ; Functionalizations ; Human immunoglobulin g ; Label-free biosensing ; Label-free detection ; Organic thin film transistors ; Protein recognition
Publicat a:	Advanced functional materials, Vol. 24, issue 40 (Oct. 2014) , p. 6291-6302, ISSN 1616-3028

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Registre creat el 2020-09-14, darrera modificació el 2022-09-10