Organic-based field effect transistors for protein detection fabricated by inkjet-printing
Martínez-Domingo, Carme (Institut de Microelectrònica de Barcelona)
Conti, Silvia (Institut de Microelectrònica de Barcelona)
De La Escosura-Muñiz, Alfredo (Institut Català de Nanociència i Nanotecnologia)
Terés, Lluís (Institut de Microelectrònica de Barcelona)
Merkoçi, Arben (Institut Català de Nanociència i Nanotecnologia)
Ramon, Eloi (Institut de Microelectrònica de Barcelona)

Date:	2020
Abstract:	Biosensors based on Organic Field-Effect Transistors (OFETs) have attracted increasing attention due to the possibility of rapid, label-free, and inexpensive detection. Among all the different possibilities, inkjet-printed top-gate organic Field Effect Transistors-Based Biosensors (BioFETs) using a polymeric gate insulator have been seldom reported. In this work, a systematic investigation in terms of topographical and electrical characterization was carried out in order to find the optimal fabrication process for obtaining a reliable polymer insulator. Previous studies have demonstrated that the best electrical performance arises from the use of the perfluoropolymer Cytop™[12,13,14]. Consequently, a simple immobilization protocol was used to ensure the proper attachment of a model biomolecule onto the Cytop's hydrophobic surface whilst keeping its remarkable insulating properties with gate current in the range of dozens of pico-amperes. The top-gate inkjet-printed BioFETs presented in this study operate at threshold voltages in the range of 1-2 V and show durability even when exposed to oxygen plasma, wet amine functionalization treatments, and aqueous media. As a preliminary application, the inkjet-printed top-gate BioFETs is used for monitoring an immunoreaction by measuring changes in the drain current, paving the way for further use of this device in the immunosensing field.
Grants:	Ministerio de Ciencia e Innovación RTI2018-102070-B-C21 Ministerio de Economía y Competitividad MAT2017-87202-P Ministerio de Economía y Competitividad SEV-2013-0295 Ministerio de Economía y Competitividad RTC-2015-4184-1 Agència de Gestió d'Ajuts Universitaris i de Recerca 2017/SGR-1624
Note:	Altres ajuts: CERCA Programme/Generalitat de Catalunya.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Language:	Anglès
Document:	Article ; recerca ; Versió acceptada per publicar
Subject:	Organic electronics ; Inkjet-printing ; Thin-film transistor ; Surface functionalization
Published in:	Organic Electronics, Vol. 84 (Sep. 2020) , art. 105794, ISSN 1566-1199

DOI: 10.1016/j.orgel.2020.105794

Postprint 43 p, 1.8 MB

The record appears in these collections:
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Experimental sciences > Catalan Institute of Nanoscience and Nanotechnology (ICN2)
Articles > Research articles
Articles > Published articles