Updated guidance on the management of COVID-19 : from an American Thoracic Society/European Respiratory Society coordinated International Task Force (29 July 2020)
Bai, Chunxue (Shanghai Respiratory Research Institution)
Chotirmall, Sanjay H. (Nanyang Technological University)
Rello, Jordi (CHU Nîmes)
Alba, George A. (Harvard Medical School)
Ginns, Leo C. (Harvard Medical School)
Krishnan, Jerry A. (University of Illinois at Chicago)
Rogers, Robert (Harvard Medical School)
Bendstrup, Elisabeth (Aarhus University Hospital (Aarhus, Dinamarca))
Burgel, Pierre-Regis (Université de Paris)
Chalmers, James D. (University of Dundee)
Chua, Abigail (Stony Brook University)
Crothers, Kristina A. (University of Washington)
Duggal, Abhijit (Cleveland Clinic)
Kim, Yeon Wook (Seoul National University Bundang Hospital)
Laffey, John (National University of Ireland)
Luna, Carlos M. (Universidad de Buenos Aires)
Niederman, Michael S. (Weill Cornell Medicine)
Raghu, Ganesh (University of Washington)
Ramirez, Julio A. (University of Louisville)
Riera del Brio, Jordi (Universitat Autònoma de Barcelona. Departament de Medicina)
Roca, Oriol (Universitat Autònoma de Barcelona. Departament de Medicina)
Tamae-Kakazu, Maximiliano (Spectrum Health-Michigan State University)
Torres, Antoni (Institut d'Investigacions Biomèdiques August Pi i Sunyer)
Watkins, Richard R. (Cleveland Clinic Akron General)
Barrecheguren, Miriam (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias)
Belliato, Mirko (IRCCS Policlinico San Matteo (Pavia, Itàlia))
Chami, Hassan A. (American University of Beirut)
Chen, Rongchang (Shenzhen Institute of Respiratory Disease)
Cortes-Puentes, Gustavo A. (Mayo Clinic)
Delacruz, Charles (Yale University School of Medicine)
Hayes, Margaret M. (Beth Israel Deaconess Medical Center)
Heunks, Leo M. A. (DAmsterdam University Medical Center)
Holets, Steven R. (Mayo Clinic)
Hough, Catherine L. (Oregon Health Sciences University)
Jagpal, Sugeet (Robert Wood Johnson University Hospital)
Jeon, Kyeongman (Sungkyunkwan University School of Medicine)
Johkoh, Takeshi (Kansai Rosai Hospital)
Lee, May M. (University of Southern California)
Liebler, Janice (University of Southern California)
McElvaney, Gerry N. (Royal College of Surgeons in Ireland)
Moskowitz, Ari (Beth Israel Deaconess Medical Center)
Oeckler, Richard A. (Mayo Clinic)
Ojanguren, Iñigo (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias)
O'Regan, Anthony (National University of Ireland)
Pletz, Mathias W. (Jena University Hospital (Alemanya))
Rhee, Chin Kook (The Catholic University of Korea)
Schultz, Marcus J. (Amsterdam UMC. University Medical Center)
Storti, Enrico (Ospedale Maggiore di Lodi)
Strange, Charlie (Medical University of South Carolina)
Thomson, Carey C. (Harvard Medical School)
Torriani, Francesca J. (UC San Diego)
Wang, Xun (People's Hospital of Nanjing Medical University)
Wuyts, Wim A (University Hospitals Leuven (Bèlgica))
Xu, Tao (Qingdao University)
Yang, Dawei (Shanghai Respiratory Research Institution)
Zhang, Ziqiang (DTongji Hospital Tongji University)
Wilson, Kevin C. (Boston University School of Medicine)

Data:	2020
Resum:	Coronavirus disease 2019 (COVID-19) is a disease caused by severe acute respiratory syndrome-coronavirus-2. Consensus suggestions can standardise care, thereby improving outcomes and facilitating future research. An International Task Force was composed and agreement regarding courses of action was measured using the Convergence of Opinion on Recommendations and Evidence (CORE) process. 70% agreement was necessary to make a consensus suggestion. The Task Force made consensus suggestions to treat patients with acute COVID-19 pneumonia with remdesivir and dexamethasone but suggested against hydroxychloroquine except in the context of a clinical trial; these are revisions of prior suggestions resulting from the interim publication of several randomised trials. It also suggested that COVID-19 patients with a venous thromboembolic event be treated with therapeutic anticoagulant therapy for 3 months. The Task Force was unable to reach sufficient agreement to yield consensus suggestions for the post-hospital care of COVID-19 survivors. The Task Force fell one vote shy of suggesting routine screening for depression, anxiety and post-traumatic stress disorder. The Task Force addressed questions related to pharmacotherapy in patients with COVID-19 and the post-hospital care of survivors, yielding several consensus suggestions. Management options for which there is insufficient agreement to formulate a suggestion represent research priorities. For patients with acute COVID-19 pneumonia who require oxygen support, the International Task Force made suggestions for remdesivir and dexamethasone, but against hydroxychloroquine. Post-discharge management of COVID-19 survivors is a research priority.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	CODIV-19
Publicat a:	European Respiratory Review, Vol. 29 (october 2020) , ISSN 1600-0617

DOI: 10.1183/16000617.0287-2020
PMID: 33020069

15 p, 1.3 MB

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