Peste des petits ruminants at the wildlife-livestock interface in the northern Albertine Rift and Nile Basin, East Africa
Fernández Aguilar, Xavier (University of Calgary. Department of Ecosystem and Public Health)
Mahapatra, Mana (Pirbright Institute)
Begovoeva, Mattia (Università degli Studi di Torino. Dipartimento di Scienze Veterinarie)
Kalema-Zikusoka, Gladys (Conservation Through Public Health)
Driciru, Margaret (Uganda Wildlife Authority)
Ayebazibwe, Chrisostom (Ministry of Agriculture. Animal Industries and Fisheries)
Adwok, David Solomon (Ministry of Animal Resources and Fisheries. Central Veterinary Diagnostic Laboratories)
Kock, Michael (Consultant Field Veterinary Programme. Wildlife Conservation Society)
Kabemba Lukusa, Jean-Paul (Regional Gorilla Conservation Employees Health Program)
Muro, Jesus (Daktari)
Marco, Ignasi (Universitat Autònoma de Barcelona. Servei d'Ecopatologia de Fauna Salvatge)
Colom Cadena, Andreu (Universitat Autònoma de Barcelona. Servei d'Ecopatologia de Fauna Salvatge)
Espunyes, Johan (Universitat Autònoma de Barcelona. Servei d'Ecopatologia de Fauna Salvatge)
Meunier, Natascha (University of London. Royal Veterinary College)
Cabezón Ponsoda, Óscar (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal)
Caron, Alexandre (Veterinary Faculty. Eduardo Mondlane University)
Bataille, Arnaud (Université Montpellier.)
Libeau, Genevieve (Université Montpellier)
Parekh, Krupali (Pirbright Institute)
Parida, Satya (Pirbright Institute)
Kock, Richard (University of London. Royal Veterinary College)

Date:	2020
Abstract:	In the recent past, peste des petits ruminants (PPR) emerged in East Africa causing outbreaks in small livestock across different countries, with evidences of spillover to wildlife. In order to understand better PPR at the wildlife-livestock interface, we investigated patterns of peste des petits ruminants virus (PPRV) exposure, disease outbreaks, and viral sequences in the northern Albertine Rift. PPRV antibodies indicated a widespread exposure in apparently healthy wildlife from South Sudan (2013) and Uganda (2015, 2017). African buffaloes and Uganda kobs <1-year-old from Queen Elizabeth National Park (2015) had antibodies against PPRV N-antigen and local serosurvey captured a subsequent spread of PPRV in livestock. Outbreaks with PPR-like syndrome in sheep and goats were recorded around the Greater Virunga Landscape in Kasese (2016), Kisoro and Kabale (2017) from western Uganda, and in North Kivu (2017) from eastern Democratic Republic of the Congo (DRC). This landscape would not be considered typical for PPR persistence as it is a mixed forest-savannah ecosystem with mostly sedentary livestock. PPRV sequences from DRC (2017) were identical to strains from Burundi (2018) and confirmed a transboundary spread of PPRV. Our results indicate an epidemiological linkage between epizootic cycles in livestock and exposure in wildlife, denoting the importance of PPR surveillance on wild artiodactyls for both conservation and eradication programs.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Published in:	Viruses, Vol. 12 Núm. 3 (2020) , p. 293, ISSN 1999-4915

Adreça alternativa: https://www.mdpi.com/1999-4915/12/3/293
DOI: 10.3390/v12030293
PMID: 32156067

19 p, 2.7 MB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Centre de Recerca en Sanitat Animal (CReSA-IRTA)
Articles > Research articles
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