Contribution of sex on the underlying mechanism of the gambling disorder severity
Jiménez-Murcia, Susana (Institut d'Investigació Biomèdica de Bellvitge)
Granero, Roser (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut)
Giménez, Mónica (Centro de Investigación Biomédica en Red de Salud Mental)
Del Pino-Gutiérrez, Amparo (Universitat de Barcelona. Departament d'Infermeria de Salut Pública, Salut Mental i Maternoinfantil)
Mestre-Bach, Gemma (Hospital Universitari de Bellvitge)
Mena Moreno, Teresa (Hospital Universitari de Bellvitge)
Moragas, Laura (Hospital Universitari de Bellvitge)
Baño, Marta (Hospital Universitari de Bellvitge)
Sánchez-González, Jéssica (Hospital Universitari de Bellvitge)
de Gracia, Marta (Hospital Universitari de Bellvitge)
Baenas Soto, Isabel Maria (Hospital Universitari de Bellvitge)
Contaldo, S. Fabrizio (Hospital Universitari de Bellvitge)
Valenciano-Mendoza, Eduardo (Centro de Investigación Biomédica en Red de Salud Mental)
Mora-Maltas, Bernat (Hospital Universitari de Bellvitge)
López-González, Hibai (Hospital Universitari de Bellvitge)
Menchón, José M. (Centro de Investigación Biomédica en Red de Salud Mental)
Fernández-Aranda, Fernando (Institut d'Investigació Biomèdica de Bellvitge)

Data:	2020
Resum:	Significant increasing prevalences have been observed in gambling disorder (GD) in the last decades. This study analyzed the underlying mechanisms of the gambling severity with path analysis (implemented through Structural Equation Modeling, SEM), and assessed the potential moderator effect of the patients' sex. A sample of n = 512 treatment-seeking patients was assessed for sociodemographics and clinical state previously to the treatment. Results obtained in two separate SEM (for men and women) revealed differences in the direct effects and the mediational links. Among the male subsample, higher GD severity was directly related to the higher cognitive bias and the younger age of onset of the problematic gambling, while impulsivity levels and age of onset achieved an indirect effect on the disordered gambling mediated by the cognitive bias. Among females, GD severity was directly increased by younger age of onset, higher cognitive bias and lower self-directedness, while lower socioeconomic positions, and higher levels in harm avoidance achieved an indirect effect on the gambling severity mediated also by the distortions related to the gambling activity. These results provide new empirical evidence for a better understanding of the GD etiology, suggesting that the underlying complex links mediating the GD severity are strongly related to the patients' sex. The results can also contribute to design more effectiveness and precise therapy programs of patient-centered care.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Translational research ; Psychology
Publicat a:	Scientific reports, Vol. 10 (october 2020) , ISSN 2045-2322

DOI: 10.1038/s41598-020-73806-6
PMID: 33127941

13 p, 1.4 MB

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