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Use of dialysis, tracheostomy, and extracorporeal membrane oxygenation among 842,928 patients hospitalized with COVID-19 in the United States
Burn, Edward (Centre for Statistics in Medicine, University of Oxford)
Sena, Anthony G. (Department of Medical Informatics, Erasmus University Medical Center (Holanda))
Prats-Uribe, Albert (University of Oxford. Centre for Statistics in Medicine)
Spotnitz, Matthew (Department of Biomedical Informatics, Columbia University)
DuVall, Scott (University of Utah School of Medicine)
Lynch, Kristine E. (Department of Internal Medicine, University of Utah School of Medicine)
Matheny, Michael E. (Department of Biomedical Informatics, Vanderbilt University Medical Center)
Nyberg, Fredrik (School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg)
Ahmed, Waheed-Ul-Rahman (College of Medicine and Health, University of Exeter)
Alser, Osaid (Massachusetts General Hospital (Boston))
Alghoul, Heba (Faculty of Medicine, Islamic University of Gaza, Palestine)
Alshammari, Thamir (Medication Safety Research Chair, King Saud University)
Zhang, Lin (School of Population and Global Health, The University of Melbourne)
Casajust, Paula (Trial Form Support (Barcelona))
Areia, Carlos (Nuffield Department of Clinical Neurosciences, University of Oxford)
Shah, Karishma (Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Botnar Research Centre)
Reich, Christian (Real World Solutions (Estats Units d'Amèrica))
Blacketer, Clair (Janssen Research & Development (Estats Units d'Amèrica))
Andryc, Alan (Janssen Research & Development (Estats Units d'Amèrica))
Fortin, Stephen (Janssen Research & Development (Estats Units d'Amèrica))
Natarajan, Karthik (Department of Biomedical Informatics, Columbia University)
Gong, Mengchun (Southern Medical University, Guangzhou, China)
Golozar, Asieh (Johns Hopkins Bloomberg School of Public Health)
Morales, Daniel (Division of Population Health and Genomics, University of Dundee)
Rijnbeek, Peter (Department of Medical Informatics, Erasmus University Medical Center)
Subbian, Vignesh (College of Engineering, The University of Arizona, Tucson)
Roel, Elena (Institut Universitari d'Investigació en Atenció Primària Jordi Gol)
Recalde, Martina (Universitat Autònoma de Barcelona)
Lane, Jennifer C. E. (Centre for Statistics in Medicine, University of Oxford)
Vizcaya, David (Bayer Pharmaceuticals (Barcelona))
Posada, Jose D. (Department of Medicine, Stanford University)
Shah, Nigam H. (Department of Medicine, Stanford University)
Jonnagaddala, Jitendra (School of Public Health and Community Medicine (Austràlia))
Lai, Lana Yin Hui (University of Manchester)
Avilés-Jurado, Francesc Xavier (Agència de Gestió d'Ajuts Universitaris i de Recerca)
Hripcsak, George (Department of Biomedical Informatics, Columbia University)
Suchard, Marc A. (Department of Biostatistic, UCLA Fielding School of Public Health, University of California)
Ranzani, Otavio T. (Pulmonary Division, Heart Institute Universidade de Sao Paulo)
Ryan, Patrick (Columbia University)
Prieto-Alhambra, Daniel (Centre for Statistics in Medicine, University of Oxford)
Kostka, Kristin (Real World Solutions (Estats Units d'Amèrica))
Duarte-Salles, Talita 1985- (Institut Universitari d'Investigació en Atenció Primària Jordi Gol)

Data: 2021
Resum: To estimate the proportion of patients hospitalized with COVID-19 who undergo dialysis, tracheostomy, and extracorporeal membrane oxygenation (ECMO). A network cohort study. Seven databases from the United States containing routinely-collected patient data: HealthVerity, Premier, IQVIA Hospital CDM, IQVIA Open Claims, Optum EHR, Optum SES, and VA-OMOP. Patients hospitalized with a clinical diagnosis or a positive test result for COVID-19. Dialysis, tracheostomy, and ECMO. 842,928 patients hospitalized with COVID-19 were included (22,887 from HealthVerity, 77,853 from IQVIA Hospital CDM, 533,997 from IQVIA Open Claims, 36,717 from Optum EHR, 4,336 from OPTUM SES, 156,187 from Premier, and 10,951 from VA-OMOP). Across the six databases, 35,192 (4. 17% [95% CI: 4. 13% to 4. 22%]) patients received dialysis, 6,950 (0. 82% [0. 81% to 0. 84%]) had a tracheostomy, and 1,568 (0. 19% [95% CI: 0. 18% to 0. 20%]) patients underwent ECMO over the 30 days following hospitalization. Use of ECMO was more common among patients who were younger, male, and with fewer comorbidities. Tracheostomy was broadly used for a similar proportion of patients regardless of age, sex, or comorbidity. While dialysis was generally used for a similar proportion among younger and older patients, it was more frequent among male patients and among those with chronic kidney disease. Use of dialysis among those hospitalized with COVID-19 is high at around 4%. Although less than one percent of patients undergo tracheostomy and ECMO, the absolute numbers of patients who have undergone these interventions is substantial.
Ajuts: European Commission. Horizon 2020 806968
Instituto de Salud Carlos III CD19/00110
Drets: Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. Creative Commons
Llengua: Anglès
Document: Article ; recerca ; Versió publicada
Publicat a: medRxiv, february 2021

DOI: 10.1101/2020.11.25.20229088
PMID: 33269356


13 p, 619.1 KB

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Documents de recerca > Documents dels grups de recerca de la UAB > Centres i grups de recerca (producció científica) > Ciències de la salut i biociències > Institut d'Investigació en Ciencies de la Salut Germans Trias i Pujol (IGTP)
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 Registre creat el 2022-02-07, darrera modificació el 2024-05-04



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