The European ME/CFS Biomarker Landscape project : an initiative of the European network EUROMENE
Scheibenbogen, Carmen (Charité - Universitätsmedizin Berlin)
Freitag, Helma (Charité - Universitätsmedizin Berlin)
Blanco, Julià (Universitat de Vic)
Capelli, Enrica (University of Pavia)
Lacerda, Eliana (London School of Hygiene & Tropical Medicine)
Authier, Jerome (Paris Est-Creteil University)
Meeus, Mira (University of Antwerp)
Castro-Marrero, Jesús (Hospital Universitari Vall d'Hebron)
Nora-Krukle, Zaiga (Riga Stradins University)
Oltra, Elisa (Centro de Investigación Príncipe Felipe (València))
Strand, Elin Bolle (Copenhagen University Hospital Rigshospitalet)
Shikova, Evelina (National Center of Infectious and Parasitic Diseases)
Sekulic, Slobodan (Medical Faculty Novi Sad)
Murovska, Modra (Riga Stradins University)
Universitat Autònoma de Barcelona

Data:	2017
Resum:	Myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) is a common and severe disease with a considerable social and economic impact. So far, the etiology is not known, and neither a diagnostic marker nor licensed treatments are available yet. The EUROMENE network of European researchers and clinicians aims to promote cooperation and advance research on ME/CFS. To improve diagnosis and facilitate the analysis of clinical trials surrogate markers are urgently needed. As a first step for developing such biomarkers for clinical use a database of active biomarker research in Europe was established called the ME/CFS EUROMENE Biomarker Landscape project and the results are presented in this review. Further we suggest strategies to improve biomarker development and encourage researchers to take these into consideration for designing and reporting biomarker studies.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Biomarker ; ME/CFS ; European network ; Landscape project ; Diagnostic ; Autoantibodies ; Autoimmunity ; B cell ; Cytokines ; Viral
Publicat a:	Journal of translational medicine, Vol. 15 (july 2017) , ISSN 1479-5876

DOI: 10.1186/s12967-017-1263-z
PMID: 28747192

7 p, 1.0 MB

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