Related Factors of Anemia in Critically Ill Patients : A Prospective Multicenter Study
Juárez-Vela, Raúl (Universidad de La Rioja)
Andrés-Esteban, Eva María (Universidad Rey Juan Carlos)
Gea-Caballero, Vicente (Universidad Internacional de Madrid)
Sánchez-González, Juan Luis (Universidad de Salamanca)
Marcos Neira, Pilar (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Serrano-Lázaro, Ainhoa (Hospital Clínic Universitari (València))
Tirado-Anglés, Gabriel (Hospital Royo Villanova)
Ruiz-Rodriguez, Juan Carlos (Hospital Universitari Vall d'Hebron)
Durante, Ángela (Universidad de La Rioja)
Santolalla-Arnedo, Iván (Universidad de La Rioja)
García-Erce, José Antonio (Banco de sangre y tejidos, Pamplona)
Quintana Diaz, Manuel (Hospital Universitario La Paz (Madrid))
Universitat Autònoma de Barcelona

Date:	2022
Abstract:	Anemia is common in critically ill patients; almost 95% of patients admitted to intensive care units (ICUs) have hemoglobin levels below normal. Several causes may explain this phenomenon as well as the tendency to transfuse patients without adequate cause: due to a lack of adherence to protocols, lack of supervision, incomplete transfusion request forms, or a lack of knowledge about the indications, risks, and costs of transfusions. Daily sampling to monitor the coagulation parameters and the acid-base balance can aggravate anemia as the main iatrogenic factor in its production. We studied the association and importance of iatrogenic blood loss and other factors in the incidence of anemia in ICUs. We performed a prospective, observational, multicenter study in five Spanish hospitals. A total of 142 patients with a median age of 58 years (IQI: 48-69), 71. 83% male and 28. 17% female, were admitted to ICUs without a diagnosis of iatrogenic anemia. During their ICU stay, anemia appeared in 66. 90% of the sample, 95 patients, (95% CI: 58. 51-74. 56%). Risk factors associated with the occurrence of iatrogenic anemia were arterial catheter insertion (72. 63% vs. 46. 81%, p -value = 0. 003), venous catheter insertion (87. 37% vs. 72. 34%, p -value = 0. 023), drainages (33. 68% vs. 12. 77%, p -value = 0. 038), and ICU stay, where the longer the stay, the higher the rate of iatrogenic anemia (p -value < 0. 001). We concluded that there was a statistical significance in the production of iatrogenic anemia due to the daily sampling for laboratory monitoring and critical procedures in intensive care units. The implementation of patient blood management programs could address these issues.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Anemia ; Blood ; Practice management ; Medical
Published in:	Journal of clinical medicine, Vol. 11 (february 2022) , ISSN 2077-0383

DOI: 10.3390/jcm11041031
PMID: 35207301

9 p, 8.2 MB

The record appears in these collections:
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut d'Investigació en Ciencies de la Salut Germans Trias i Pujol (IGTP)
Articles > Research articles
Articles > Published articles