Percutaneous mitral valve repair : Outcome improvement with operator experience and a second-generation device
Freixa, X. (Hospital Clínico Universitario Virgen de la Arrixaca (El Palmar, Múrcia))
Estevez-Loureiro, Rodrigo (Hospital Universitario de León)
Carrasco-Chinchilla, Fernando (Hospital Universitario Virgen de la Victoria (Màlaga, Andalusia))
Millán, X. (Institut d'Investigació Biomèdica Sant Pau)
Amat-Santos, Ignacio J (Hospital Clínico Universitario de Valladolid)
Regueiro, Ander (Hospital Clínico Universitario Virgen de la Arrixaca (El Palmar, Múrcia))
Nombela-Franco, L. (Hospital Clínico San Carlos (Madrid))
Pascual, I. (Hospital Universitario Central de Asturias)
Cid-Álvarez, Belén (Complejo Hospitalario Universitario de Santiago de Compostela)
López-Mínguez, José Ramón (Hospital Universitario Infanta Cristina)
Hernández-Antolín, R.A. (Hospital Universitario Ramón y Cajal (Madrid))
Cruz-González, Ignacio (Hospital Clínico Universitario (Salamanca))
Andraka, L. (Hospital Civil de Basurto)
Goicolea, J. (Hospital Universitario Puerta de Hierro Majadahonda (Madrid))
Ruíz-Quevedo, V. (Complejo Hospitalario de Navarra)
Díez, J.L. (Hospital Universitari i Politècnic La Fe (València))
Berenguer, Alberto (Hospital General Universitario de Valencia)
Baz, J.A. (Complejo Hospitalario Universidad de Vigo)
Pan, M. (Hospital Universitario Reina Sofía (Còrdova, Espanya))
Benito-González, Tomás (Hospital Universitario de León)
Alonso Briales, J.H. (Hospital Universitario Virgen de la Victoria (Màlaga, Andalusia))
Li, Chi Hion (Institut d'Investigació Biomèdica Sant Pau)
Sanchis, L. (Hospital Clínico Universitario Virgen de la Arrixaca (El Palmar, Múrcia))
Serrador, A. (Hospital Clínico Universitario de Valladolid)
Jiménez-Quevedo, P. (Hospital Clínico San Carlos (Madrid))
Avanzas, Pablo (Hospital Universitario Central de Asturias)
Salido, L. (Hospital Universitario Ramón y Cajal (Madrid))
Fernández-Vázquez, Felipe (Hospital Universitario de León)
Hernández-García, J.M. (Hospital Universitario Virgen de la Victoria (Màlaga, Andalusia))
Arzamendi, Dabit (Institut d'Investigació Biomèdica Sant Pau)

Date:	2021
Abstract:	Background and aim: Recent randomized data comparing percutaneous mitral valve repair (PMVR) versus optimal medical treatment in patients with functional MR (FMR) seemed to highlight the importance of the learning curve not only for procedural outcomes but also for patient selection. The aim of the study was to compare a contemporary series of patients undergoing PMVR using a second-generation Mitraclip device (Mitraclip NT) with previous cohorts treated with a first-generation system. Methods: This multicenter study collected individual data from 18 centers between 2012 and 2017. The cohort was divided into three groups according to the use of the first-generation Mitraclip during the first (control-1) or second half (control-2) or the Mitraclip NT sys-tem. Results: A total of 545 consecutive patients were included in the study. Among all, 182 (33. 3%), 183 (33. 3%), and 180 (33. 3%) patients underwent mitral repair in the control-1, control-2, and NT cohorts, respectively. Procedural success was achieved in 93. 3% of patients without differences between groups. Major adverse events did not statistically differ among groups, but there was a higher rate of pericardial effusion in the control-1 group (4. 3%, 0. 6%, and 2. 6%, respectively; p = 0. 025). The composite endpoint of death, surgery, and admission for congestive heart failure (CHF) at 12 months was lower in the NT group (23. 5% in control-1, 22. 5% in control-2, and 8. 3% in the NT group; p = 0. 032). Conclusions: The present paper shows that contemporary clinical outcomes of patients undergoing PMVR with the Mitraclip system have improved over time.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Transcatheter mitral valve repair ; Mitral regurgitation ; MitraClip
Published in:	Journal of clinical medicine, Vol. 10 Núm. 4 (february 2021) , p. 1-10, ISSN 2077-0383

DOI: 10.3390/jcm10040734
PMID: 33673247

11 p, 3.8 MB

The record appears in these collections:
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut de Recerca Sant Pau
Articles > Research articles
Articles > Published articles