Analysis of metabolic dynamics during drought stress in Arabidopsis plants
Lozano Elena, Fidel (Centre de Recerca en Agrigenòmica)
Fábregas, Norma (Vetgenomics)
Coleto-Alcudia, Vereda (Centre de Recerca en Agrigenòmica)
Caño Delgado, Ana I (Centre de Recerca en Agrigenòmica)

Date:	2022
Abstract:	Drought is a major cause of agricultural losses worldwide. Climate change will intensify drought episodes threatening agricultural sustainability. Gaining insights into drought response mechanisms is vital for crop adaptation to climate emergency. To date, only few studies report comprehensive analyses of plant metabolic adaptation to drought. Here, we present a multifactorial metabolomic study of early-mid drought stages in the model plant Arabidopsis thaliana. We sampled root and shoot tissues of plants subjected to water withholding over a six-day time course, including brassinosteroids receptor mutants previously reported to show drought tolerance phenotypes. Furthermore, we sequenced the root transcriptome at basal and after 5 days drought, allowing direct correlation between metabolic and transcriptomic changes and the multi-omics integration. Significant abiotic stress signatures were already activated at basal conditions in a vascular-specific receptor overexpression (BRL3ox). These were also rapidly mobilized under drought, revealing a systemic adaptation strategy driven from inner tissues of the plant. Overall, this dataset provides a significant asset to study drought metabolic adaptation and allows its analysis from multiple perspectives.
Grants:	European Commission 683163 European Commission 612583 Ministerio de Ciencia e Innovación BIO2016-78150-P Ministerio de Ciencia e Innovación CEX2019-000902-S Ministerio de Economía y Competitividad SEV-2015-0533 Ministerio de Economía y Competitividad BIO2013-43873
Note:	Altres ajuts: we acknowledge support from the CERCA Programme/Generalitat de Catalunya
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Metabolomics ; Molecular engineering in plants ; Transcriptomics
Published in:	Scientific data, Vol. 9 (2022) , art. 90, ISSN 2052-4463

DOI: 10.1038/s41597-022-01161-4
PMID: 35314705

12 p, 3.4 MB

The record appears in these collections:
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Experimental sciences > CRAG (Centre for Research in Agricultural Genomics)
Articles > Research articles
Articles > Published articles