Volume-dependent hemodynamic effects of blood collection in canine donors - Evaluation of 13% and 15% of total blood volume depletion
Ferreira, R.R.F. (Universidade do Porto. Departamento de Clínicas Veterinárias)
Ruiz de Gopegui i Fernández, Rafael (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)
de Matos, Augusto J. F (Unidade Multidisciplinar de Investigação em Biomedicina)

Data:	2015
Resum:	Background: There is no consensus regarding the blood volume that could be safely donated by dogs, ranging from 11 to 25% of its total blood volume (TBV). No previous studies evaluated sedated donors. Aim: To evaluate the hemodynamic effects of blood collection from sedated and non-sedated dogs and to understand if such effects were volume-dependent. Materials and Methods: Fifty three donations of 13% of TBV and 20 donations of 15% TBV were performed in dogs sedated with diazepam and ketamine. Additionally, a total of 30 collections of 13% TBV and 20 collections of 15% TBV were performed in nonsedated dogs. Non-invasive arterial blood pressures and pulse rates were registered before and 15 min after donation. Results: Post-donation pulse rates increased significantly in both sedated groups, with higher differences in the 15% TBV collections. Systolic arterial pressures decreased significantly in these groups, while diastolic pressures increased significantly in 13% TBV donations. Non-sedated groups revealed a slight, but significant, SBP decrease. No clinical signs related to donations were registered. Conclusion: These results suggest that the collection of 15% TBV in sedated donors induces hemodynamic variations that may compromise the harmlessness of the procedure, while it seems to be a safe procedure in non-sedated dogs.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Blood donation ; Dog sedation ; Volume
Publicat a:	Anais da Academia Brasileira de Ciencias, Vol. 87 Núm. 1 (january 2015) , p. 381-388, ISSN 1678-2690

DOI: 10.1590/0001-3765201520140210
PMID: 25651153

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