Paper-based biosensors for cancer diagnostics
Pereira, Claudia (Institut Català de Nanociència i Nanotecnologia)
Parolo, Claudio (Institut Català de Nanociència i Nanotecnologia)
Idili, Andrea (Institut Català de Nanociència i Nanotecnologia)
Gomis, Roger R.. (Institut de Recerca Biomèdica)
Rodrigues, Lígia (Universidade do Minho. Centro de Engenharia Biológica)
Sales, Goreti (Universidade de Coimbra. Departmento de Enginharia Química)
Merkoçi, Arben (Institut Català de Nanociència i Nanotecnologia)

Date:	2022
Abstract:	The implementation of a wide diagnostic campaign to diagnose cancer early could save millions of lives and billions of dollars every year. Unfortunately, cancer diagnosis is extremely complicated and current approaches rely on the use of expensive equipment and specialized personnel, which hamper their deployment in low- and middle-income settings. Here, we analyze the technical challenges that must be overcome to achieve precise cancer diagnostics and we describe how such hurdles have limited the development of point-of-care (PoC) sensors. Then, we explain why we believe recent achievements in the field of paper-based sensors could allow their use as widely available sensing platforms for cancer detection. Finally, we present our vision of what should be done in order to make paper-based sensors widely used diagnostics platforms for cancer.
Grants:	European Commission 754510 Agencia Estatal de Investigación CEX2018-000806-S Agencia Estatal de Investigación MAT2017-87202-P Agencia Estatal de Investigación SEV-22013-0295
Note:	Altres ajuts: this work is also funded by the CERCA Program/Generalitat de Catalunya.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Language:	Anglès
Document:	Article ; recerca ; Versió sotmesa a revisió
Subject:	Paper-based sensors ; Cancer screening ; Early diagnosis ; Point-of-care diagnostics ; Nanobiosensors
Published in:	Trends in Chemistry, Vol. 4, issue 6 (June 2022) , p. 554-567, ISSN 2589-5974

DOI: 10.1016/j.trechm.2022.03.005

Preprint 32 p, 1.1 MB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Experimental sciences > Catalan Institute of Nanoscience and Nanotechnology (ICN2)
Articles > Research articles
Articles > Published articles