Mapping Chilean clinical research : A protocol for a scoping review and multiple evidence gap maps
Bracchiglione, Javier (Interdisciplinary Centre for Health Studies (CIESAL). Universidad de Valparaíso)
Meza, Nicolas (Interdisciplinary Centre for Health Studies (CIESAL). Universidad de Valparaíso)
Franco, Juan Victor Ariel (Institute of General Practice. Heinrich-Heine-University Düsseldorf)
Escobar Liquitay, Camila Micaela (Research Department. Instituto Universitario Hospital Italiano de Buenos Aires)
Munoz, Sergio R. (Department of Public Health-CIGES. Universidad de la Frontera)
Urrútia, Gerard (Institut d'Investigació Biomèdica Sant Pau)
Madrid, Eva (Interdisciplinary Centre for Health Studies (CIESAL). Universidad de Valparaíso)

Data:	2022
Resum:	Introduction Clinical research broadly aims to influence decision-making in order to promote appropriate healthcare. Funding agencies should prioritise research projects according to needed research topics, methodological and cost-effectiveness considerations, and expected social value. In Chile, there is no local diagnosis regarding recent clinical research that might inform prioritisation for future research funding. This research aims to comprehensively identify and classify Chilean health research studies, elaborating evidence gap maps for the most burdensome local conditions. Methods and analysis We will search in electronic databases (MEDLINE, Embase, PsycINFO, CINAHL, LILACS and WoS) and perform hand searches to retrieve, identify and classify health research studies conducted in Chile or by authors whose affiliations are based in Chile, from 2000 onwards. We will elaborate evidence matrices for the 20 conditions with the highest burden in Chile (according to the Global Burden of Disease 2019) selected from those defined under the General Regime of the Health Guarantees Act. To elaborate the evidence gap maps, we will consider prioritised interventions and core outcome sets. To identify knowledge gaps and estimate redundant research, we will contrast these gap maps with the available international evidence of high or moderate certainty of evidence, for each specific clinical question. For this purpose, we will search systematic reviews using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach. Ethics and dissemination No ethical approval is required to conduct this project. We will submit our results in both peer-reviewed journals and scientific conferences. We will aim to disseminate our findings through different academic platforms, social media, local press, among others. The final results will be communicated to local funding agencies and government stakeholders. Discussion We aim to provide an accurate and up-to-date picture of the research gaps - to be filled by new future findings - and the identification of redundant research, which will constitute relevant information for local decision-makers.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article de revisió ; recerca ; Versió publicada
Publicat a:	BMJ open, Vol. 12 Núm. 6 (january 2022) , p. e057555, ISSN 2044-6055

DOI: 10.1136/bmjopen-2021-057555
PMID: 35725258

8 p, 421.9 KB

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Documents de recerca > Documents dels grups de recerca de la UAB > Centres i grups de recerca (producció científica) > Ciències de la salut i biociències > Institut de Recerca Sant Pau
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