How to Identify Invasive Candidemia in ICU-A Narrative Review
Alves, Joana (Hospital de Braga)
Alonso-Tarrés, Carles (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Rello, Jordi (Clinical Research, CHU Nîmes)

Fecha:	2022
Resumen:	The incidence of invasive fungal infection in ICUs has increased over time, and Candida spp. is the most common cause. Critical care patients are a particular set of patients with a higher risk of invasive fungal infections; this population is characterized by extensive use of medical devices such as central venous lines, arterial lines, bladder catheters, hemodialysis and mechanical intubation. Blood cultures are the gold standard diagnosis; still, they are not an early diagnostic technique. Mannan, anti-mannan antibody, 1,3-β-D-glucan, Candida albicans germ tube antibody, Vitek 2, PNA-FISH, MALDI-TOF, PCR and T2Candida panel are diagnostic promising microbiological assays. Scoring systems are tools to distinguish patients with low and high risk of infection. They can be combined with diagnostic tests to select patients for pre-emptive treatment or antifungal discontinuation. Candidemia is the focus of this narrative review, an approach to contributing factors and diagnosis, with an emphasis on critical care patients.
Derechos:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Lengua:	Anglès
Documento:	Article ; recerca ; Versió publicada
Materia:	Critical care patients ; Intensive care units ; Invasive fungal infection ; Candidemia
Publicado en:	Antibiotics, Vol. 11, Issue 12 (December 2022) , art. 1804, ISSN 2079-6382

DOI: 10.3390/antibiotics11121804
PMID: 36551461

15 p, 544.5 KB

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