One Health Approach : Invasive California Kingsnake (Lampropeltis californiae) as an Important Source of Antimicrobial Drug-Resistant Salmonella Clones on Gran Canaria Island
Santana-Hernández, Kevin M. (Universidad de Las Palmas de Gran Canaria. Departamento de Patología Animal)
Rodríguez-Ponce, Eligia (Universidad de Las Palmas de Gran Canaria. Departamento de Patología Animal)
Medina, Inmaculada Rosario (Universidad de Las Palmas de Gran Canaria. Instituto Universitario de Sanidad Animal)
Acosta-Hernández, Begoña (Universidad de Las Palmas de Gran Canaria. Instituto Universitario de Sanidad Animal)
Priestnall, Simon L. (University of London. Royal Veterinary College (Hatfield, Regne Unit))
Vega, Santiago (Universidad Cardenal Herrera-CEU. Instituto de Ciencias Biomédicas)
Marín Orenga, Clara (Universidad Cardenal Herrera-CEU. Instituto de Ciencias Biomédicas)
Cerdà-Cuéllar, Marta (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal)
Marco-Fuertes, Ana (Universidad Cardenal Herrera-CEU. Instituto de Ciencias Biomédicas)
Ayats, Teresa (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal)
García Beltrán, Teresa (Universidad de Las Palmas de Gran Canaria. Instituto Universitario de Sanidad Animal)
Lupiola-Gómez, Pablo A. (Universidad de Las Palmas de Gran Canaria. Departamento de Ciencias Clínicas)

Date:	2023
Abstract:	The aim of this study was to investigate the invasive species Lampropeltis californiae (California kingsnake) as a reservoir of Salmonella and its ability to spread different clones of the bacterium with zoonotic potential into the environment, as well as study its antimicrobial resistance patterns in Gran Canaria (Spain). The main results showed that a high diversity of Salmonella subsp. salamae strains circulate in Gran Canaria with a high prevalence of resistance shown for antimicrobials of public health importance, as summarised in the European Decision 2013/652/EU. The increase in the reptile population has led to a rise in the number of zoonotic infections due to close contact with reptiles, with reptile-associated salmonellosis being particularly relevant. California kingsnake invasion not only threatens the endemic reptile population of the island of Gran Canaria (Spain) but also poses serious public health problems by spreading zoonotic pathogens and their antimicrobial resistance (AMR) to the environment. Thus, the aim of this study was to assess the occurrence, genetic diversity, and AMR among Salmonella spp. strains isolated from California kingsnakes in Gran Canaria Island (Spain). Of 73 invasive individuals captured, 20. 5% carried Salmonella spp. , belonging to different subspecies and serovars, with subsp. salamae as the most abundant. Pulsed-field electrophoresis showed high genetic diversity among subsp. salamae isolates, and among these, 73. 3% showed resistance to at least one of the antimicrobials tested. In conclusion, the present study revealed the importance of wild invasive California kingsnakes as reservoirs of drug-resistant Salmonella spp. that could pose a direct threat to livestock and humans. Identification of drug-resistant Salmonella strains in wildlife provides valuable information on potential routes of transmission that involve risks to public and animal health.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Salmonella ; Multi-drug resistance ; PFGE ; Lampropeltis californiae
Published in:	Animals, Vol. 13 (may 2023) , ISSN 2076-2615

DOI: 10.3390/ani13111790
PMID: 37889724

12 p, 2.0 MB

The record appears in these collections:
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Centre de Recerca en Sanitat Animal (CReSA-IRTA)
Articles > Research articles
Articles > Published articles