Hospital-acquired influenza infections detected by a surveillance system over six seasons, from 2010/2011 to 2015/2016
Godoy, Pere
Torner, Núria
Soldevila, Núria (Universitat de Barcelona)
Rius i Gibert, Maria Cristina (Agència de Salut Pública de Barcelona)
Jané, Mireia (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública)
Martínez, Ana
Caylà, Joan A
Domínguez, Ángela (Universitat de Barcelona)
Alsedà, Miquel
Álvarez, Josep
Arias, César
Balaña, Pilar Jorgina
Barrabeig, Irene
Camps, Neus
Carol, Mónica
Ferràs, Joaquim
Ferrús, Glòria
Follia, Núria
Bach Foradada, Pilar
Minguell, Sofia
Parrón, Ignacio
Plasència, Elsa
Sala-Farré, Maria Rosa
Torra i Bastardas, Roser
Torres, J.
Caylà, Joan A
Gorrindo, Pilar
Marcos, María Ángeles
Mosquera, Maria del Mar
Vilella-Figuerola, Alba (Institut d'Investigació Biomèdica Sant Pau)
Antón, Andrés
Pumarola Suñé, Tomàs
Campins Martí, Magda
Garciá, D.
Espejo, Elena
Freixas, Núria
Riera Garcia, Montserrat
Maraver, Encarna
Mas, Dolors
Perez, Rafael
Rebull Fatsini, Josep
Pou, J.
Garciá-Pardo, Graciano
Olona, Montserrat
Barcenilla, Fernando
Castellana, Dolors
Navarro Rubio, Gemma
Force, Lluís
Universitat Autònoma de Barcelona

Data:	2020
Resum:	In addition to outbreaks of nosocomial influenza, sporadic nosocomial influenza infections also occur but are generally not reported in the literature. This study aimed to determine the epidemiologic characteristics of cases of nosocomial influenza compared with the remaining severe cases of severe influenza in acute hospitals in Catalonia (Spain) which were identified by surveillance. An observational case-case epidemiological study was carried out in patients aged ≥18 years from Catalan 12 hospitals between 2010 and 2016. For each laboratory-confirmed influenza case (nosocomial or not) we collected demographic, virological and clinical characteristics. We defined patients with nosocomial influenza as those admitted to a hospital for a reason other than acute respiratory infection in whom ILI symptoms developed ≥48 h after admission and influenza virus infection was confirmed using RT-PCR. Mixed-effects regression was used to estimate the crude and adjusted OR. One thousand seven hundred twenty-two hospitalized patients with severe laboratory-confirmed influenza virus infection were included: 96 (5. 6%) were classified as nosocomial influenza and more frequently had > 14 days of hospital stay (42. 7% vs. 27. 7%, P <. 001) and higher mortality (18. 8% vs. 12. 6%, P <. 02). The variables associated with nosocomial influenza cases in acute-care hospital settings were chronic renal disease (aOR 2. 44 95% CI 1. 44-4. 15) and immunodeficiency (aOR 1. 79 95% CI 1. 04-3. 06). Nosocomial infections are a recurring problem associated with high rates of chronic diseases and death. These findings underline the need for adherence to infection control guidelines.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Healthcare-associated infection ; Hospitalized patients ; Influenza ; Nosocomial infection
Publicat a:	BMC Infectious diseases, Vol. 20 Núm. 1 (28 2020) , p. 80, ISSN 1471-2334

DOI: 10.1186/s12879-020-4792-7
PMID: 31992207

7 p, 513.1 KB

El registre apareix a les col·leccions:
Documents de recerca > Documents dels grups de recerca de la UAB > Centres i grups de recerca (producció científica) > Ciències de la salut i biociències > Institut de Recerca Sant Pau
Articles > Articles de recerca
Articles > Articles publicats