Lack of detection of Mycobacterium microti infection in wild rodents from a free-ranging wild boar outbreak area
Vidal Barba, Enric (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal)
Espunyes, Johan (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)
Puig Ribas, Maria (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)
Melgarejo, Cristian (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal)
Martino, Laura (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal)
Michelet, Lorraine (Paris-Est University National. Reference Laboratory for Tuberculosis)
Boschiroli, Maria Laura (Paris-Est University National. Reference Laboratory for Tuberculosis)
Sanz, Albert (Generalitat de Catalunya. Departament d'Acció Climàtica, Agricultura i Agenda Rural)
Allepuz Palau, Alberto (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals)
Cabezón Ponsoda, Óscar (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)
Pérez de Val, Bernat (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal)

Date:	2023
Abstract:	Wild small rodents are considered the natural reservoirs of Mycobacterium microti, a member of the Mycobacterium tuberculosis complex (MTBC) that can cause tuberculosis (TB) in humans and animals, as well as interfere with current tuberculosis eradication plans in livestock. A cross-sectional study was carried out in the Catalan Pyrenees (Iberian Peninsula) in an area where M. microti was previously isolated from wild boars, to evaluate the role of micromammals in the epidemiology of this outbreak. A total of 350 wild rodents were necropsied (306 Murinae and 44 Arvicolinae) in spring and autumn during two consecutive natural years. Tissues were analyzed by histopathology to look for TB-like lesions and by qPCR and culture to detect MTBC. Sera were analyzed by MTBC-specific ELISA. No evidence of TB infection in wild rodents was confirmed. Results suggest that small rodents did not play a role in the epidemiology of M. microti in the area. The source of this mycobacterium remains unknown, but previous detections of M. microti in various species in southern France suggest the movements of wild boars across the French Pyrenees as the most likely origin of the outbreak detected in the Iberian Peninsula.
Note:	Altres ajuts: acords transformatius de la UAB. Departament d'Acció Climàtica, Agricultura i Agenda Rural de la Generalitat de Catalunya EFA357/INNOTUB (Program Interreg POCTEFA 2004-2020)
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Micromammals ; Mycobacterium tuberculosis complex ; Pyrenees ; Tuberculosis ; Vole ; Wildlife ; SDG 3 - Good Health and Well-being
Published in:	European Journal of Wildlife Research, Vol. 69 Núm. 6 (2023) , p. 111, ISSN 1439-0574

Adreça original del document, elimineu-la del registre: https://egreta.uab.cat/ws/files/389201544/s10344-023-01738-3.pdf
DOI: 10.1007/s10344-023-01738-3

6 p, 1.1 MB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Centre de Recerca en Sanitat Animal (CReSA-IRTA)
Articles > Research articles
Articles > Published articles