Epidemiological and clinical characteristics of children hospitalized due to influenza A and B in the south of Europe, 2010-2016
Jané i Checa, Mireia (Instituto de Salud Carlos III)
Vidal, Maria José (Agència de Salut Pública de Catalunya)
Soldevila, Núria (Universitat de Barcelona)
Romero, Arancha (Universitat de Barcelona)
Martínez, Ana (Instituto de Salud Carlos III)
Torner, Nuria (Instituto de Salud Carlos III)
Godoy, Pere (Instituto de Salud Carlos III)
Launes, Cristian (Sant Joan de Deu Children's Hospital)
Rius i Gibert, Maria Cristina (Agència de Salut Pública de Barcelona)
Marcos, Maria Angeles (Hospital Clínic i Provincial de Barcelona)
Domínguez, Ángela (Universitat de Barcelona)
Universitat Autònoma de Barcelona

Date:	2019
Abstract:	Influenza produces annual epidemics that affect 5-15% of the world population. Complications and hospitalizations are more frequent in childhood. This study describes and analyses the epidemiological and clinical characteristics of children hospitalized due to confirmed influenza in influenza surveillance sentinel hospitals in Catalonia. Retrospective descriptive study conducted in six influenza seasons (2010-2011 to 2015-2016) in persons aged 0-17 years diagnosed with laboratory-confirmed influenza requiring hospitalization. 291 cases were notified to the health authorities: 79. 4% were due to the influenza A virus and 20. 6% to the B virus. The most common subtype was H1N1 with 57. 6% of cases: 52. 6% were male, 56. 7% were aged <2 years, and 24. 4% were aged <1 year. 62. 2% of cases had pneumonia, 26. 8% acute respiratory distress syndrome and 11. 7% bacterial pneumonia. 5. 8% of cases were vaccinated and 21. 3% required intensive care unit admission, of whom 54. 8% were aged <2 years. There were 3 deaths, all with influenza A infection. Influenza A cases were younger than influenza B cases (OR 3. 22; 95% CI: 1. 73-6. 00). Conclusion: Children aged <2 years are especially vulnerable to the A H1N1 virus, including those without pre-existing chronic disease. These results are relevant for the planning of vaccination programs to improve maternal and child health.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Influenza virus ; Paediatrics
Published in:	Scientific reports, Vol. 9 Núm. 1 (january 2019) , p. 12853, ISSN 2045-2322

DOI: 10.1038/s41598-019-49273-z
PMID: 31492899

7 p, 875.8 KB

The record appears in these collections:
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut de Recerca Sant Pau
Articles > Research articles
Articles > Published articles