Potential business model for a European vaccine R&D infrastructure and its estimated socio-economic impact
Jungbluth, Stefan (European Vaccine Initiative)
Martin, William (European Vaccine Initiative)
Slezak, Monika (European Vaccine Initiative)
Depraetere, Hilde (European Vaccine Initiative)
Guzman, Carlos A. (Helmholtz Centre for Infection Research)
Ussi, Anton (EATRIS- European Research Infrastructure for Translational Medicine)
Morrow, David (EATRIS- European Research Infrastructure for Translational Medicine)
Van Heuverswyn, Fran (Flanders Vaccine)
Arnouts, Sven (Ghent University)
Carrondo, Manuel J. T. (Instituto de Biologia Experimental e Tecnológica)
Olesen, Ole (European Vaccine Initiative)
Ottenhoff, Tom H.M. (Leiden University Medical Center)
Dockrell, H. M. (London School of Hygiene & Tropical Medicine)
Ho, Mei Mei (Medicines and Healthcare products Regulatory Agency)
Dobly, Alexandre (Sciensano)
Christensen, Dennis (Statens Serum Institut)
Segalés Coma, Joaquim (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal)
Laurent, Fabrice (Université François Rabelais de Tours)
Lantier, Frédéric (Université François Rabelais de Tours)
Stockhofe-Zurwieden, Norbert (Wageningen Bioveterinary Research)
Morelli, Francesca (CIRMMP)
Langermans, Jan A.M. (Biomedical Primate Research Centre)
Verreck, Frank A.W. (Biomedical Primate Research Centre)
Le Grand, Roger (Université Paris-Saclay)
Sloots, Arjen (Intravacc)
Medaglini, Donata (University of Siena)
Lawrenz, Maria (Vaccine Formulation Institute)
Collin, Nicolas (Vaccine Formulation Institute)

Date:	2023
Abstract:	Research infrastructures are facilities or resources that have proven fundamental for supporting scientific research and innovation. However, they are also known to be very expensive in their establishment, operation and maintenance. As by far the biggest share of these costs is always borne by public funders, there is a strong interest and indeed a necessity to develop alternative business models for such infrastructures that allow them to function in a more sustainable manner that is less dependent on public financing. In this article, we describe a feasibility study we have undertaken to develop a potentially sustainable business model for a vaccine research and development (R&D) infrastructure. The model we have developed integrates two different types of business models that would provide the infrastructure with two different types of revenue streams which would facilitate its establishment and would be a measure of risk reduction. For the business model we are proposing, we have undertaken an ex ante impact assessment that estimates the expected impact for a vaccine R&D infrastructure based on the proposed models along three different dimensions: health, society and economy. Our impact assessment demonstrates that such a vaccine R&D infrastructure could achieve a very significant socio-economic impact, and so its establishment is therefore considered worthwhile pursuing. The business model we have developed, the impact assessment and the overall process we have followed might also be of interest to other research infrastructure initiatives in the biomedical field.
Grants:	European Commission. Horizon 2020 951668
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Vaccines ; Research and development ; Research infrastructure ; Business model ; Sustainability ; Impact assessment ; Science policy
Published in:	F1000Research, Vol. 12 (october 2023) , ISSN 2046-1402

DOI: 10.12688/f1000research.141399.1
PMID: 38298529

26 p, 1021.9 KB

The record appears in these collections:
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Centre de Recerca en Sanitat Animal (CReSA-IRTA)
Articles > Research articles
Articles > Published articles