The potential of CO2-based production cycles in biotechnology to fight the climate crisis
Bachleitner, Simone (University of Natural Resources and Life Sciences. Department of Biotechnology (Austria))
Ata, Özge (University of Natural Resources and Life Sciences. Department of Biotechnology (Austria))
Mattanovich, Diethard (University of Natural Resources and Life Sciences. Department of Biotechnology (Austria))

Data:	2023
Resum:	Rising CO2 emissions have pushed scientists to develop new technologies for a more sustainable bio-based economy. Microbial conversion of CO2 and CO2-derived carbon substrates into valuable compounds can contribute to carbon neutrality and sustainability. Here, we discuss the potential of C1 carbon sources as raw materials to produce energy, materials, and food and feed using microbial cell factories. We provide an overview of potential microbes, natural and synthetic C1 utilization pathways, and compare their metabolic driving forces. Finally, we sketch a future in which C1 substrates replace traditional feedstocks and we evaluate the costs associated with such an endeavor.
Ajuts:	European Commission 101000441
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Applied microbiology ; Industrial microbiology ; Metabolic engineering ; Synthetic biology
Publicat a:	Nature communications, Vol. 14 (November 2023) , art. 6978, ISSN 2041-1723

DOI: 10.1038/s41467-023-42790-6
PMID: 37914683

9 p, 975.3 KB

Supplementary material 11 p, 48.4 KB

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