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18 p, 1.7 MB The Expression of Cellular Prion Protein, PrPC, Favors pTau Propagation and Blocks NMDAR Signaling in Primary Cortical Neurons / Rivas-Santisteban, Rafael (Universitat de Barcelona. Institut de Neurociències) ; Raïch, Iu (Universitat de Barcelona. Departament de Bioquímica i Fisiologia) ; Aguinaga Andrés, David (Universitat de Barcelona. Departament de Bioquímica i Biomedicina Molecular) ; Saura Antolín, Carlos (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Franco, Rafael (Universitat de Barcelona. Facultat de Química) ; Navarro Brugal, Gemma (Universitat de Barcelona. Departament de Bioquímica i Fisiologia)
Background: The N-methyl-D-aspartate receptor (NMDAR) is a target in current treatments for Alzheimer's disease (AD). The human prion protein (PrPC) has an important role in the pathophysiology of AD. [...]
2023 - 10.3390/cells12020283
Cells, Vol. 12 (january 2023)  
Detailed record - Creative Commons

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