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1.
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12 p, 503.9 KB |
Excellent Response to OnabotulinumtoxinA : Different Definitions, Different Predictors
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Ornello, Raffaele (University of L'Aquila) ;
Baraldi, Carlo (AOU Policlinico di Modena) ;
Ahmed, Fayyaz (Hull University Teaching Hospitals) ;
Negro, Andrea (Sapienza University) ;
Miscio, Anna Maria (Fondazione IRCCS "Casa Sollievo Della Sofferenza") ;
Santoro, Antonio (Fondazione IRCCS "Casa Sollievo Della Sofferenza") ;
Alpuente, Alicia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Russo, Antonio (University of Campania "Luigi Vanvitelli") ;
Silvestro, Marcello (University of Campania "Luigi Vanvitelli") ;
Cevoli, Sabina (IRCCS Istituto delle Scienze Neurologiche di Bologna) ;
Brunelli, Nicoletta (Campus Bio-Medico University Hospital (Itàlia)) ;
Vernieri, Fabrizio (Campus Bio-Medico University Hospital (Itàlia)) ;
Grazzi, Licia (IRCCS Foundation "Carlo Besta" Neurological Institute) ;
Pani, Luca (VeraSci (Estats Units d'Amèrica)) ;
Andreou, Anna P (Guy's and St Thomas' NHS Foundation Trust (Regne Unit)) ;
Lambru, Giorgio (Guy's and St Thomas' NHS Foundation Trust (Regne Unit)) ;
Frattale, Ilaria (Tor Vergata University) ;
Kamm, Katharina (Ludwig Maximilians University München) ;
Ruscheweyh, Ruth (Ludwig Maximilians University München) ;
Russo, Marco (Azienda USL-IRCCS di Reggio Emilia) ;
Torelli, Paola (University of Parma) ;
Filatova, Elena (Sechenov First Moscow State Medical University) ;
Latysheva, Nina (Sechenov First Moscow State Medical University) ;
Gryglas-Dworak, Anna (Headache Center Wroclaw) ;
Straburzyński, Marcin (University of Warmia and Mazury) ;
Butera, Calogera (IRCCS San Raffaele Scientific Institute (Milà, Itàlia)) ;
Colombo, Bruno (IRCCS San Raffaele Scientific Institute (Milà, Itàlia)) ;
Filippi, Massimo (IRCCS San Raffaele Scientific Institute (Milà, Itàlia)) ;
Pozo-Rosich, Patricia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Martelletti, Paolo (Sapienza University) ;
Guerzoni, Simona (University of Modena and Reggio Emilia) ;
Sacco, Simona (University of L'Aquila) ;
Universitat Autònoma de Barcelona
The identification of patients who can benefit the most from the available preventive treatments is important in chronic migraine. We explored the rate of excellent responders to onabotulinumtoxinA in a multicenter European study and explored the predictors of such response, according to different definitions. [...]
2022 -  10.3390/ijerph191710975
International journal of environmental research and public health, Vol. 19 (september 2022)
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2.
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12 p, 2.1 MB |
European headache federation consensus on the definition of resistant and refractory migraine
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Sacco, Simona (Regional Referral Headache Center of the Abruzzo region) ;
Braschinsky, Mark (Tartu University Clinics) ;
Ducros, Anne (University Hospital of Montpellier (França)) ;
Lampl, Christian (Hospital Barmherzige Brüder) ;
Little, Patrick (European Migraine & Hendrik Ido Ambacht) ;
van den Brink, Antoinette Maassen (Erasmus MC University Medical Center Rotterdam) ;
Pozo-Rosich, Patricia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Reuter, Uwe (Charité - Universitätsmedizin Berlin) ;
de la Torre, Elena Ruiz (Hendrik Ido Ambacht) ;
Del Rio, Margarita Sanchez (Clínica Universidad de Navarra) ;
Sinclair, Alexandra J. (Birmingham Health Partners) ;
Katsarava, Zaza (IM Sechenov First Moscow State Medical University) ;
Martelletti, Paolo (Sant'Andrea Hospital) ;
Universitat Autònoma de Barcelona
Despite advances in the management of headache disorders, some patients with migraine do not experience adequate pain relief with acute and preventive treatments. It is the aim of the present document to provide a definition of those migraines which are difficult-to-treat, to create awareness of existence of this group of patients, to help Healthcare Authorities in understanding the implications, and to create a basis to develop a better pathophysiological understanding and to support further therapeutic advances. [...]
2020 - 10.1186/s10194-020-01130-5
Journal of headache and pain, Vol. 21 (june 2020)
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3.
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18 p, 1.1 MB |
Burden of Migraine in Patients With Preventive Treatment Failure Attending European Headache Specialist Centers : Real-World Evidence From the BECOME Study
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Pozo-Rosich, Patricia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Lucas, Christian (Hôpital Salengro) ;
Watson, David P. B. (Hamilton Medical Group) ;
Gaul, Charly (Migraine and Headache Clinic Königstein) ;
Ramsden, Emma (Novartis Pharma AG) ;
Ritter, Shannon (Novartis Pharmaceuticals Corporation) ;
Martelletti, Paolo (Regional Referral Headache Center, Sant'Andrea Hospital) ;
Snellman, Josefin (Novartis Pharma AG) ;
Universitat Autònoma de Barcelona
Migraine is consistently ranked as one of the most disabling neurological conditions in the world, often causing a substantial impairment of daily activities and quality of life. It also carries a high economic burden of direct and indirect healthcare costs. [...]
2021 - 10.1007/s40122-021-00331-3
Pain and Therapy, Vol. 10 (october 2021) , p. 1691-1708
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4.
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14 p, 810.0 KB |
Is There a Gender Difference in the Response to onabotulinumtoxinA in Chronic Migraine? Insights from a Real-Life European Multicenter Study on 2879 Patients
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Ornello, Raffaele (University of L'Aquila. Department of Applied Clinical Sciences and Biotechnology) ;
Ahmed, Fayyaz (Hull University Teaching Hospitals. Department of Neurosciences) ;
Negro, Andrea (Sapienza University. Department of Clinical and Molecular Medicine) ;
Miscio, Anna Maria (Fondazione IRCCS "Casa Sollievo della Sofferenza". Unit of Neurology) ;
Santoro, Antonio (Fondazione IRCCS "Casa Sollievo della Sofferenza". Unit of Neurology) ;
Alpuente, Alicia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Russo, Antonio (University of Campania "Luigi Vanvitelli". Department of Medical, Surgical, Neurological, Metabolic, and Aging Sciences) ;
Silvestro, Marcello (University of Campania "Luigi Vanvitelli". Department of Medical, Surgical, Neurological, Metabolic, and Aging Sciences) ;
Cevoli, Sabina (IRCCS Istituto delle scienze Neurologiche di Bologna) ;
Brunelli, Nicoletta (Campus Bio-Medico University Hospital. Headache and Neurosonology Unit) ;
Vernieri, Fabrizio (Campus Bio-Medico University Hospital. Headache and Neurosonology Unit) ;
Grazzi, Licia (IRCCS Foundation "Carlo Besta" Neurological Institute. Neurology Department) ;
Baraldi, Carlo (University of Modena and Reggio Emilia. Department of Biomedical, Metabolic and Neural Sciences) ;
Guerzoni, Simona (University of Modena and Reggio Emilia. Department of Biomedical, Metabolic and Neural Sciences) ;
Andreou, Anna P. (Guy's and St Thomas' NHS Foundation Trust. Headache Service) ;
Lambru, Giorgio (Guy's and St Thomas' NHS Foundation Trust. Headache Service) ;
Kamm, Katharina (Ludwig Maximilians University München. Department of Neurology) ;
Ruscheweyh, Ruth (Ludwig Maximilians University München. Department of Neurology) ;
Russo, Marco (Azienda USL-IRCCS di Reggio Emilia. Neuromotor and Rehabilitation Department) ;
Torelli, Paola (University of Parma. Headache Center) ;
Filatova, Elena (Sechenov First Moscow State Medical University (Sechenov University). Department of Neurology) ;
Latysheva, Nina (Sechenov First Moscow State Medical University (Sechenov University). Department of Neurology) ;
Gryglas-Dworak, Anna (Headache Center Wroclaw) ;
Straburzyński, Marcin (Headache Clinic (Warsaw, Poland)) ;
Butera, Calogera (IRCCS San Raffaele Scientific Institute. Neurophysiology Service) ;
Colombo, Bruno (IRCCS San Raffaele Scientific Institute (Milà, Itàlia). Neurology Unit) ;
Filippi, Massimo (IRCCS San Raffaele Scientific Institute. Neurorehabilitation Unit) ;
Pozo-Rosich, Patricia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Martelletti, Paolo (Sapienza University. Department of Clinical and Molecular Medicine) ;
Sacco, Simona (University of L'Aquila. Department of Applied Clinical Sciences and Biotechnology) ;
Universitat Autònoma de Barcelona
Migraine is mostly a female disorder because of its lower prevalence in men. Less than 20% of patients included in the available studies on migraine treatments are men; hence, the evidence on migraine treatments might not apply to men. [...]
2021 - 10.1007/s40122-021-00328-y
Pain and Therapy, Vol. 10 (september 2021) , p. 1605-1618
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5.
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14 p, 1.3 MB |
Diagnosis and management of migraine in ten steps
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Eigenbrodt, Anna K. (University of Copenhagen) ;
Ashina, Håkan (University of Copenhagen) ;
Khan, Sabrina (University of Copenhagen) ;
Diener, Hans-Christoph (University Duisburg-Essen) ;
Mitsikostas, Dimos D. (Aeginition Hospital) ;
Sinclair, Alexandra J. (Birmingham Women's and Children's Hospital (Regne Unit)) ;
Pozo-Rosich, Patricia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Martelletti, Paolo (Sant'Andrea Hospital) ;
Ducros, Anne (University Hospital of Montpellier (França)) ;
Lantéri-Minet, Michel (Centre Hospitalo-Universitaire de Nice) ;
Braschinsky, Mark (Tartu University Hospital (Tartu, Estònia)) ;
Del Rio, Margarita Sanchez (Clínica Universidad de Navarra) ;
Daniel, Oved (Headache & Facial Pain Clinic) ;
Özge, Aynur (Mersin University Medical Faculty) ;
Mammadbayli, Ayten (Azerbaijan State Medical University, Baku, Azerbaijan) ;
Arons, Mihails (eStradins University) ;
Skorobogatykh, Kirill (University Headache Clinic, Moscow, Russia) ;
Romanenko, Vladimir (Ukrainian Institute of Family Medicine) ;
Terwindt, Gisela M. (Leiden University Medical Center) ;
Paemeleire, Koen (Universitair Ziekenhuis Gent) ;
Sacco, Simona (University of L'Aquila) ;
Reuter, Uwe (Charité - Universitätsmedizin Berlin) ;
Lampl, Christian (Ordensklinikum Linz) ;
Schytz, Henrik W. (University of Copenhagen) ;
Katsarava, Zaza (IM Sechenov First Moscow State Medical University) ;
Steiner, Timothy J. (Imperial College London) ;
Ashina, Messoud (Azerbaijan Medical University)
Migraine is a disabling primary headache disorder that directly affects more than one billion people worldwide. Despite its widespread prevalence, migraine remains under-diagnosed and under-treated. [...]
2021 - 10.1038/s41582-021-00509-5
Nature Reviews. Neurology, Vol. 17 (june 2021) , p. 501-514
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6.
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10 p, 2.3 MB |
Burden and attitude to resistant and refractory migraine : a survey from the European Headache Federation with the endorsement of the European Migraine & Headache Alliance
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Sacco, Simona (ASL Avezzano-Sulmona-L'Aquila) ;
Lampl, Christian (Hospital Barmherzige Brüder) ;
Maassen van den Brink, Antoinette (Erasmus MC University Medical Center Rotterdam) ;
Caponnetto, Valeria (ASL Avezzano-Sulmona-L'Aquila) ;
Ducros, Anne (University Hospital of Montpellier (França)) ;
Little, Patrick (European Migraine & Headache Alliance (EMHA), Brussels) ;
Pozo-Rosich, Patricia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Reuter, Uwe (Charité - Universitätsmedizin Berlin) ;
Ruiz de la Torre, Elena (European Migraine & Headache Alliance (EMHA), Brussels) ;
Sánchez Del Rio, Margarita (Clínica Universidad de Navarra) ;
Sinclair, Alexandra J. (Birmingham Health Partners) ;
Martelletti, Paolo (Sant'Andrea Hospital) ;
Katsarava, Zaza (IM Sechenov First Moscow State Medical University) ;
Universitat Autònoma de Barcelona
New treatments are currently offering new opportunities and challenges in clinical management and research in the migraine field. There is the need of homogenous criteria to identify candidates for treatment escalation as well as of reliable criteria to identify refractoriness to treatment. [...]
2021 - 10.1186/s10194-021-01252-4
Journal of headache and pain, Vol. 22 (may 2021)
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7.
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14 p, 826.8 KB |
Early Management of OnabotulinumtoxinA Treatment in Chronic Migraine : Insights from a Real-Life European Multicenter Study
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Ornello, Raffaele (University of L'Aquila. Neuroscience Section, Department of Applied Clinical Sciences and Biotechnology) ;
Ahmed, Fayyaz (Hull University Teaching Hospitals) ;
Negro, Andrea (Sapienza University) ;
Miscio, Anna Maria (Fondazione IRCCS "Casa Sollievo Della Sofferenza") ;
Santoro, Antonio (Fondazione IRCCS "Casa Sollievo Della Sofferenza") ;
Alpuente, Alicia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Russo, Antonio (University of Campania "Luigi Vanvitelli") ;
Silvestro, Marcello (University of Campania "Luigi Vanvitelli".) ;
Cevoli, Sabina (IRCCS Istituto Delle Scienze Neurologiche Di Bologna) ;
Brunelli, Nicoletta (Campus Bio-Medico University Hospital) ;
Vernieri, Fabrizio (Campus Bio-Medico University Hospital) ;
Grazzi, Licia (IRCCS Foundation "Carlo Besta" Neurological Institute) ;
Baraldi, Carlo (University of Modena and Reggio Emilia) ;
Guerzoni, Simona (University of Modena and Reggio Emilia) ;
Andreou, Anna P. (Guy's and St Thomas' NHS Foundation Trust) ;
Lambru, Giorgio (Guy's and St Thomas' NHS Foundation Trust) ;
Frattale, Ilaria (Tor Vergata University) ;
Kamm, Katharina (Ludwig Maximilians University München) ;
Ruscheweyh, Ruth (Ludwig Maximilians University München) ;
Russo, Marco (Azienda USL-IRCCS Di Reggio Emilia) ;
Torelli, Paola (University of Parma) ;
Filatova, Elena (Sechenov First Moscow State Medical University) ;
Latysheva, Nina (Sechenov First Moscow State Medical University) ;
Gryglas-Dworak, Anna (Headache Center Wroclaw) ;
Straburzynski, Marcin (Terapia Neurologiczna Samodzielni) ;
Butera, Calogera (IRCCS San Raffaele Scientific Institute (Milà, Itàlia)) ;
Colombo, Bruno (IRCCS San Raffaele Scientific Institute (Milà, Itàlia)) ;
Filippi, Massimo (IRCCS San Raffaele Scientific Institute (Milà, Itàlia)) ;
Pozo-Rosich, Patricia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Martelletti, Paolo (Sapienza University'Andrea) ;
Sacco, Simona (University of L'Aquila) ;
Universitat Autònoma de Barcelona
OnabotulinumtoxinA (BT-A) quarterly was the first treatment approved specifically for chronic migraine (CM). It is unclear whether three cycles are better than two to assess early BT-A response. We performed a retrospective analysis on real-life prospectively collected data in 16 European headache centers. [...]
2021 - 10.1007/s40122-021-00253-0
Pain and Therapy, Vol. 10 (march 2021) , p. 637-650
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8.
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10 p, 964.3 KB |
Guideline on the use of onabotulinumtoxinA in chronic migraine : a consensus statement from the European Headache Federation
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Bendtsen, Lars (University of Copenhagen) ;
Sacco, Simona (University of L'Aquila. Neuroscience Section, Department of Applied Clinical Sciences and Biotechnology) ;
Ashina, Messoud (University of Copenhagen) ;
Mitsikostas, Dimos (National and Kapodistrian University of Athens. 1st Department of Neurology, Aeginition Hospital) ;
Ahmed, Fayyaz (Hull York Medical School. Department of Neurosciences) ;
Pozo-Rosich, Patricia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Martelletti, Paolo (Sapienza University. Department of Clinical and Molecular Medicine) ;
Universitat Autònoma de Barcelona ;
Hospital Universitari Vall d'Hebron
OnabotulinumtoxinA is being increasingly used in the management of chronic migraine (CM). Treatment with onabotulinumtoxinA poses challenges compared with traditional therapy with orally administered preventatives. [...]
2018 - 10.1186/s10194-018-0921-8
Journal of headache and pain, Vol. 19 (september 2018)
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